Figure 3. Growth inhibition of Plasmodium parasites by antibody pools from the 3-antigen and 7-antigen immunisation groups.

The 7-antigen immunisation group (Gp 1) had only a single sample (antibodies purified from a pool of 98 rabbit sera), hence a direct comparison of the functional activities of antibodies from the 3 and 7-antigen immunisation groups could not be made. The growth inhibitory activity of IgGs purified from a pool of all rabbits immunised with DiCo mix (3-antigen, Gp 2) in the same adjuvant (CoVaccine HT™) was therefore compared with that of the single Gp 1 sample against the FCR3, HB3 and NF54 parasite strains. Plots represent the mean % inhibition ± SEM for replicate measurements for each sample. Blue filled circles (•) represent the Gp 1 pooled sample and the red filled squares (▪) represent the Gp 2 pooled sample.