Table 1.
CcO activity in synaptic and nonsynaptic mitochondria from Tg mAPP mice and non-Tg mice
| Age | Non-Tg nonsynaptic mitochondria | Non-Tg synaptic mitochondria | APP nonsynaptic mitochondria | APP synaptic mitochondria |
| 4 mo | 133.8 ± 11.88 | 147.8 ± 14.12 | 136.45 ± 10.28 | 113.18 ± 2.19* |
| 12 mo | 134.59 ± 4.84 | 129.68 ± 6.65 | 101.92 ± 5.85** | 89.67 ± 5.29*** |
CcO activity is measured in nmol/mg of mitochondrial fraction per minute (n = 7–15 mice per group).
*P < 0.05 vs. other mitochondrial fractions.
**P < 0.05 vs. 12-mo-old non-Tg mitochondrial fractions.
***P < 0.05 vs. other mitochondrial fractions.