Table 1.

NF-kB pathway genes found mutated in DLBCL

Gene Symbol (alias)	N. of mutated/tested cases (%)
	ABC-DLBCL	GCB-DLBCL	non-GC/NC DLBCL
TNFAIP3 (A20)	9/37 (24.3%)	1/44 (2.3%)	4/20 (20%)
CARD11	4/37 (10.8%)	3/44 (6.8%)*	2/20 (10%)
TNFRSF11A (RANK)	3/37 (8.1%)^	1/44 (2.3%)	2/20 (10%)
TRAF5	2/37 (5.4%)	2/44 (4.5%)	1/20 (5%)
TRAF2	1/37 (2.7%)	4/44 (9.1%)**	1/20 (5%)
MAP3K7 (TAK1)	2/37 (5.4%)	0/44	0/20
ALL GENES	19/37 (51.3%)	10/44 (22.7%)***	7/20 (35%)

^{^}One additional cell line was found to carry a mutation in a minority of the population

^*Two of the 3 mutated samples are cell lines; analysis restricted to exons 4-9, encoding the coiled-coil domain

^**Three of the 4 mutated samples are cell lines

^***Four of the 10 mutated samples are cell lines