Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Nov 4;6(11):e1001178. doi: 10.1371/journal.ppat.1001178

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Slater et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

HBECs were transfected with siRNA specific for RIG-I or control siRNA, infected with RV1B and RIG-I protein (A) and mRNA (B) measured. HBECs were transfected with MDA5 specific siRNA or control siRNA and infected with RV1B and MDA5 protein (C) and mRNA (D) measured. HBECs were transfected with siRNA specific for TLR3 or control siRNA and infected with RV1B and TLR3 protein (E) and mRNA (F) measured. HBECs were transfected with siRNA specific for TRIF or control siRNA and infected with RV1B and TRIF protein (G) and mRNA (H) measured. *p<0.05, **p<0.01, ***p<0.001 versus control siRNA or as indicated. mRNA data was generated from 6 independent experiments utilizing 3 independent HBEC donors, 2 experiments per donor.