Table 2.
Chronic Kidney Disease Prevalence and Mean Glomerular Filtration Rate according to Patients Characteristics and Risk Factors for Stroke, CHUV, 2001-2003, N = 890
| Characteristic and risk factors for stroke | Number N (%) |
Chronic Kidney Disease N (%) |
P value | Mean (SD) GFR ml/min/1.73 m2 |
P value | |||
|---|---|---|---|---|---|---|---|---|
| I | II | III | IV-V | |||||
| N (%) | 890 (100.0) | 59 (6.6) | 469 (52.7) | 335 (37.6) | 27 (3.0) | 64.3 (17.8) | ||
| Age | < 0.001 | < 0.001 | ||||||
| ≤60 years | 240 (27.0) | 39 (16.3) | 177 (73.8) | 20 (8.3) | 4 (1.7) | 76.8 (16.5) | ||
| 60-70 years | 151 (17.0) | 10 (6.6) | 92 (60.9) | 47 (31.1) | 2 (1.3) | 67.4 (16.2) | ||
| 71-80 years | 267 (30.0) | 8 (3.0) | 121 (45.3) | 127 (47.6) | 11 (4.1) | 59.1 (15.8) | ||
| < 80 years | 232 (26.0) | 2 (0.86) | 79 (34) | 141 (61) | 10 (4.3) | 55.2 (13.9) | ||
| Gender | < 0.001 | < 0.001 | ||||||
| Male | 479 (53.8) | 52 (10.9) | 287 (59.9) | 126 (26.3) | 14 (2.9) | 69.1 (18.7) | ||
| Female | 411 (46.2) | 7 (1.7) | 182 (44.3) | 209 (50.9) | 13 (3.2) | 58.6 (14.8) | ||
| Risk Factors for stroke | ||||||||
| Hypertension | 528 (59.3) | 22 (4.2) | 246 (46.6) | 239 (45.3) | 21 (3.9) | < 0.001 | 60.3 (16.9) | < 0.001 |
| Diabetes | 133 (15.0) | 11 (8.3) | 51 (38.3) | 64 (48.1) | 7 (5.3) | 0.003 | 59.6 (19.7) | 0.003 |
| Hyper-Cholesterolemia | 346 (38.9) | 20 (5.8) | 181 (52.3) | 135 (39) | 10 (2.9) | 0.812 | 63.7 (17.0) | 0.47 |
| Smoking | < 0.001 | < 0.001 | ||||||
| No | 595 (66.8) | 24 (4.03) | 285 (48) | 268 (45.04) | 18 (3.03) | 61.1 (16.2) | ||
| Yes | 198 (22.2) | 30 (15.15) | 127 (64.1) | 37 (18.7) | 4 (2.02) | 73.7 (18.0) | ||
| Ex-smoker | 97 (11.0) | 5 (5.15) | 57 (58.8) | 30 (31) | 5 (5.15) | 64.7 (19.8) | ||
| Antecedent | ||||||||
| Ischemic Heart Disease | 126 (14.2) | 3 (2.4) | 55 (43.7) | 62 (49.2) | 6 (4.8) | 0.005 | 59.2 (16.1) | < 0.001 |
| Heart failure | 97 (11.0) | 3 (3.1) | 35 (36.1) | 54 (55.7) | 5 (5.2) | 0.0003 | 55.4 (17.6) | < 0.001 |
| Peripheral Arterial Insufficiency | 36 (4.0) | 2 (5.6) | 18 (50) | 14 (38.9) | 2 (5.6) | 0.703 | 62.4 (21.4) | 0.52 |
| Atrial Fibrillation | 125 (14.0) | 4 (3.2) | 51 (40.8) | 64 (51.2) | 6 (4.8) | 0.0017 | 57.0 (16.8) | < 0.001 |
| Positive Family History for Stroke/Heart Disease | 16 (1.8) | 4 (25) | 11 (68.8) | 1 (6.25) | 0 | 0.005 | 79.5 (15.0) | < 0.001 |
| TIA before Stroke | 77 (8.7) | 5 (6.5) | 39 (50.7) | 31 (40.3) | 2 (2.6) | 0.964 | 62.0 (17.3) | 0.25 |
| Severity of disease | ||||||||
| Functional Status | 0.006 | 0.04 | ||||||
| I | 263 (29.6) | 11(4.2) | 157 (59.7) | 92 (35) | 3 (1.14) | 65.3 (15.6) | ||
| II | 201 (22.6) | 20 (9.9) | 104 (51.7) | 71 (35.3) | 6 (3) | 65.2 (17.8) | ||
| III | 164 (18.4) | 10 (6.1) | 91 (55.5) | 54 (33) | 9 (5.5) | 65.1 (19.3) | ||
| IV | 230 (25.8) | 18 (7.8) | 104 (45.2) | 100 (43.5) | 8 (3.5) | 62.7 (19.4) | ||
| Death | 32 (3.6) | 0 | 13 (40.6) | 18 (56.3) | 1 (3.13) | 56.2 (11.6) | ||
| Charlson score | < 0.001 | < 0.001 | ||||||
| Charlson score 0 or 1 | 268 (30.1) | 18 (6.7) | 174 (65) | 74 (27.6) | 2 (0.8) | 68.8 (16.2) | ||
| Charlson score 2 | 93 (10.5) | 2 (2.2) | 47 (50.5) | 42 (45.2) | 2 (2.2) | 62.2 (14.4) | ||
| Charlson score 3 | 298 (33.5) | 23 (7.7) | 156 (52.4) | 111 (37.3) | 8 (2.7) | 64.7 (17.4) | ||
| Charlson score ≥4 | 231 (26.0) | 16 (6.9) | 92 (39.8) | 108 (46.8) | 15 (6.5) | 59.2 (19.9) | ||
TIA: Transient Ischemic Attack
GFR: Glomerular Filtration Rate ml/min/1.73 m2