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. 2010 Nov 4;5(11):e13697. doi: 10.1371/journal.pone.0013697

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Kispersky et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Parameter values are and and fixed for all diagrams. The value of is below the threshold for hyper-excitable firing and thus a theta frequency ISI is observed. Each panel shows the evolution of the phase space for time points through one firing phase. Time increases from A to H. As the trajectory evolves it is captured by the slow-manifold (vicinity of the V-nullsurface) and is forced to move around it on a slow time scale thus causing subthreshold oscillations.

Inline graphic — Parameter values are and and fixed for all diagrams. The value of is below the threshold for hyper-excitable firing and thus a theta frequency ISI is observed. Each panel shows the evolution of the phase space for time points through one firing phase. Time increases from A to H. As the trajectory evolves it is captured by the slow-manifold (vicinity of the V-nullsurface) and is forced to move around it on a slow time scale thus causing subthreshold oscillations.