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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Biochem Pharmacol. 2010 Jun 26;80(12):1771–1792. doi: 10.1016/j.bcp.2010.06.036

Figure 1. Epigenetic mechanisms involved in carcinogenesis.

Figure 1

Carcinogenesis is a long-term process and both genetic and epigenetic factors contribute to cancer development. Epigenetic changes, such as DNA methylation, histone modifications and microRNAs are easily influenced by dietary and environmental factors. Dietary polyphenols can potentially impact all three epigenetic modifications, which in turn contributes towards their chemopreventive potential.