Figure 1. Resynchronization after 1 or 4 weekly 6h phase-advances.

A. Mean group core Tb from mice resynchronizing to a 4^th 6h advance shift of the light-cycle, and control unshifted mice. The current light-dark cycle for both groups is shown at the bottom of Day 1. Note the initial 6h phase difference on Day 1, and the gradual leftward adjustment made by the shifters, until the two records overlay each other by the last day, indicating synchronization. B. A map of 7 phase markers in shifted and control mice. Shifted mice were analyzed for Day 6 after the first or the 4^th advance shift. The LPS challenge occurred on Day 7. All measures except for locomotor activity (LMA) onset are the time of the rhythm peak.