Figure 6. Altered molecular rhythms in central and peripheral tissues following CJL.
Mean (±SEM) circadian amplitude (A) and period (B) of mPer2:LUC rhythms for 4 tissues in vitro, harvested from 4-week shifted versus control mice. * p<0.05; ** p<0.01, Students t-test. C. Relative mRNA abundance of Period2 and Bmal1 in peritoneal macrophages harvested from shifted and control mice at 8 daily time points. ANOVA: Per2 Control p<0.01, Shifted: p<0.02; Bmal1 Control p=0.06, Shifted p=0.64; n=3–4 per time point for all groups.