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. Author manuscript; available in PMC: 2011 Nov 11.
Published in final edited form as: J Med Chem. 2010 Nov 11;53(21):7467–7489. doi: 10.1021/jm901742e

Figure 11.

Figure 11

A) QS inhibitors identified via high-throughput screening by Müh et al. IC50 values determined using a LasR-dependent yfp P. aeruginosa reporter strain.56 B) Structures of triphenyl compounds. EC50 values represent concentration needed for half-maximal induction of yfp fluorescence. aIC50 value for QS inhibition.