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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: J Immunol. 2010 Oct 11;185(10):6214–6225. doi: 10.4049/jimmunol.0903843

Figure 6. Activation of Kp-induced NF-κB and MAPKs in lung tissues of neutrophil depleted KC+/+ and KC-/- mice.

Figure 6

(A) Wild-type and KC-/- mice challenged with 103 CFU i.t. were euthanized at 24 and 48 h post infection and lungs were used for western blotting. The membranes were probed with activated NF-κB and MAPK Abs. (B) Densitometric analysis of Western blots from three independently performed experiments to quantify the protein levels of IKK, NF-κB, ICAM-1, VCAM-1 and phospho-IKK, -NF-κB, and -MAPKs following Kp challenge. The data obtained from these experiments were normalized against GAPDH and expressed as mean ± SE from 2 independent experiments). The significance between the KC-/- and KC+/+ mice was indicated as p < 0.05.