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Scheme representing two possible cases upon fusion. (A) newly exocytosed vesicle components (red) intermix with components resident on the plasma membrane (black), leading to the endocytosis of intermixed vesicle components. (B) newly exocytosed vesicle components (red) stay clustered and endocytosed vesicles keep their identity, although both newly exocytosed and membrane-resident components are internalized in separate vesicles.
