Table III.
Mucoadhesive agent | pH | Swollen volume (cm3/g) ± SD (n = 6) | Zeta potential (mV) ± SD (n = 6) | Mucoadhesive strength (g) ± SD (n = 6) | ||||
---|---|---|---|---|---|---|---|---|
5 min | 10 min | 15 min | 20 min | 30 min | ||||
FCM | 7.02 | 8.04 ± 0.33 | −20.54 ± 0.05 | 5.50 ± 0.39 | 5.86 ± 0.36 | 6.46 ± 0.44 | 6.89 ± 0.52 | 7.52 ± 0.61 |
HPMC | 6.73 | 7.85 ± 0.95 | 0.00 ± 0.00 | 3.63 ± 0.15 | 4.15 ± 0.09 | 4.44 ± 0.06 | 4.76 ± 0.03 | 5.25 ± 0.04 |
CP | 3.27 | 15.75 ± 0.65 | −23.64 ± 0.03 | 4.24 ± 0.08 | 4.72 ± 0.05 | 5.20 ± 0.06 | 5.36 ± 0.08 | 5.74 ± 0.09 |
FCM Ficus carica mucilage, HPMC hydroxypropylmethyl cellulose, CP Carbopol 934, SD standard deviation