Table IV.
Values of Gelation Temperature and Mechanical Properties of the Gels
| Formulation code | Gelation temperature (°C) | Hardness (g) | Adhesiveness (g) | Cohesiveness | Mucoadhesive strength (g) |
|---|---|---|---|---|---|
| FCM 5 | 27.20 ± 0.33 | 141.67 ± 2.08 | −2,560.96 ± 12.71 | 1.07 ± 0.05 | 67.56 ± 0.34 |
| FCM 5(E) | 26.50 ± 0.21 | – | – | – | – |
| FCM 10 | 24.60 ± 0.24 | 245.67 ± 2.62 | −3,628.05 ± 22.87 | 0.96 ± 0.02 | 75.25 ± 0.55 |
| FCM 10(E) | 24.20 ± 0.31 | – | – | – | – |
| FCM 15 | 22.80 ± 0.25 | 468.11 ± 2.60 | −6,644.66 ± 20.29 | 0.92 ± 0.07 | 83.75 ± 0.65 |
| FCM 15(E) | 22.40 ± 0.11 | – | – | – | – |
| CP 5 | 28.50 ± 0.02 | 135.50 ± 2.91 | −2,269.82 ± 17.67 | 1.08 ± 0.08 | 44.27 ± 0.33 |
| CP 5 (E) | 28.00 ± 0.04 | – | – | – | – |
| CP 10 | 25.50 ± 0.03 | 204.00 ± 2.24 | −3,628.09 ± 12.26 | 1.03 ± 0.02 | 62.08 ± 0.98 |
| CP 10 (E) | 25.00 ± 0.05 | – | – | – | – |
| CP 15 | 23.30 ± 0.04 | 335.00 ± 1.85 | −5,508.83 ± 9.90 | 0.93 ± 0.02 | 73.26 ± 0.53 |
| CP 15(E) | 22.80 ± 0.06 | – | – | – | – |
| HPMC 5 | 29.50 ± 0.05 | 118.00 ± 0.82 | −2,158.04 ± 17.67 | 1.04 ± 0.14 | 10.23 ± 0.95 |
| HPMC 5(E) | 29.00 ± 0.03 | – | – | – | – |
| HPMC 10 | 27.80 ± 0.11 | 175.67 ± 3.62 | −3,084.31 ± 25.92 | 1.03 ± 0.03 | 30.67 ± 1.15 |
| HPMC 10(E) | 27.20 ± 0.05 | – | – | – | – |
| HPMC 15 | 25.20 ± 0.15 | 295.00 ± 2.85 | −4,438.49 ± 30.26 | 0.96 ± 0.04 | 43.67 ± 1.13 |
| HPMC 15(E) | 24.60 ± 0.04 | – | – | – | – |
Data shows mean ± SD (n = 6)
FCM Ficus carica mucilage, HPMC hydroxypropylmethyl cellulose, CP Carbopol 934