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. 2010 Aug 10;11(3):1250–1256. doi: 10.1208/s12249-010-9489-6

Table III.

Mean Particle Size, Zeta Potential, Drug Loading, and Encapsulation Efficiency of Nanoparticles (mean ± SD, n = 3)

Formulation Mean particle size* (nm ± SD) Zeta potential (mV ± SD) Entrapment Efficiency* (%) Drug Loading (%)
DS-loaded Eudragit NP 274 ± 0.19 −1.53 ± 3.10 62.0 ± 2.41 14.26 ± 1.60
DS-loaded Eudragit:PLGA (50:50) NP 263 ± 0.12 −1.27 ± 2.81 53.1 ± 2.73 12.21 ± 3.00
DS-loaded Eudragit:PLGA (30:70) NP 247.4 ± 0.13 −0.46 ± 4.14 45.3 ± 3.00 10.51 ± 2.10
DS-loaded Eudragit:PLGA (20:80) NP 241 ± 0.18 3.47 ± 5.10 25.82 ± 2.60 5.96 ± 1.80*

DS diclofenac sodium, NP nanoparticles

* p < 0.05