Table II.

Physicomechanical Evaluation of Atenolol Buccal Patches

Formulations	Weight variationa (g)	Thicknessa (mm)	Folding endurance	Drug contenta (%)
F 1	2.06 ± 0.06	0.54 ± 0.02	81	99.50 ± 0.10
F 2	2.09 ± 0.03	0.56 ± 0.04	83	98.61 ± 0.09
F 3	2.10 ± 0.06	0.57 ± 0.04	88	99.14 ± 0.08
F 4	2.03 ± 0.05	0.53 ± 0.05	80	99.42 ± 0.12
F 5	2.02 ± 0.04	0.53 ± 0.03	86	98.87 ± 0.11
F 6	2.00 ± 0.05	0.54 ± 0.01	91	98.43 ± 0.10
F 7	2.09 ± 0.07	0.58 ± 0.02	83	98.24 ± 0.10
F 8	2.07 ± 0.08	0.56 ± 0.02	84	98.43 ± 0.12
F 9	2.10 ± 0.09	0.55 ± 0.05	82	98.61 ± 0.12
F 10	2.10 ± 0.09	0.56 ± 0.03	80	99.77 ± 0.12
F 11	2.11 ± 0.07	0.54 ± 0.04	93	99.60 ± 0.13
F 12	2.09 ± 0.09	0.53 ± 0.04	90	98.88 ± 0.10
F 13	2.06 ± 0.06	0.51 ± 0.04	92	99.51 ± 0.10
F 14	2.12 ± 0.08	0.59 ± 0.05	86	99.77 ± 0.12

^aAll values are mean ± SD, n = 3.