Table II.
Mean Temperature Shifts and Enthalpy Change of SC After Treatment with Laurocapram, Laurocapram Analogues and Iminosulfurane Formulations
| Treatments | Mean temperature shift (°C) ± SD (n = 3) | Mean enthalpy change (J/g) ± SD (n = 3) | ||||
|---|---|---|---|---|---|---|
| ΔT m1 | ΔT m2 | ΔT m3 | ΔH1 | ΔH2 | ΔH3 | |
| No treatment | – | – | – | – | – | – |
| Water | −3.0 ± 0.8a | −6.2 ± 1.7a | −1.5 ± 0.14a | −0.01 ± 0.001 | −0.03 ± 0.02 | −0.008 ± 0.003a |
| PG | −2.0 ± 0.9a | −6.0 ± 4.5a | –b | 0.4 ± 0.01 | 0.5 ± 0.01 | –b |
| Ethanol | −14.0 ± 0.01 | −6.0 ± 4.0a | +8.5 ± 0.04 | 0.4 ± 0.04 | 0.4 ± 0.09 | 0.02 ± 0.001 |
| PEG 400 | +7.0±2.2a | +2.0 ± 5.5a | –b | 0.1 ± 0.03a | 0.1 ± 0.01 | –b |
| Laurocapram | –b | −13.1 ± 0.9a | –b | –b | 0.1 ± 0.02 | –b |
| Laurocapram–water | –b | –b | −7.5 ± 1.0a | –b | –b | −0.05 ± 0.01 |
| Laurocapram–PG | −9.0 ± 4.2a | –b | −7.5 ± 5.4a | 0.05 ± 0.001 | –b | 0.5 ± 0.04 |
| Laurocapram–ethanol | −5.0 ± 1.9a | +2.0 ± 0.8a | −9.9 ± 0.7a | −0.6 ± 0.05 | −0.8 ± 0.3 | No change |
| Laurocapram–PEG 400 | −5 ± 1.6 | No change | –b | 0.7 ± 0.05 | −0.1 ± 0.01a | –b |
| N-0915–water | –b | Merger of T m1 and T m2 at 70°C | Multiple peaks at 92, 94 and100°C | –b | – | – |
| N-0915–PG | −3.0 ± 1.6 | −7.0 ± 0.5a | −6.5 ± 1.4 | 0.7 ± 0.04 | −0.1 ± 0.03 | 1.4 ± 0.4a |
| N-0915–ethanol | +9.0 ± 1.3a | +8.0 ± 0.03a | +8.5 ± 0.9 | −0.4 ± 0.02 | −1.0 ± 0.2 | No change |
| N-0915-PEG 400 | +6.0 ± 0.4a | +1.0 ± 0.3a | –b | No change | No change | –b |
| DMBIS–water | −3.0 ± 1.5a | −8.0 ± 3.7a | −9.9 ± 0.09a | −0.9 ± 0.3 | −0.7 ± 0.03 | 0.02 ± 0.008 |
| DMBIS–PG | −4.3 ± 1.2a | −10.0 ± 0.8a | −13.5 ± 4.9a | 1.0 ± 0.6 | 0.01 ± 0.01 | 0.01 ± 0.06 |
| DMBIS–ethanol | No change | No change | –b | No change | No change | –b |
| DMBIS–PEG 400 | +3.0 ± 1.4a | +2.0 ± 3.1a | +22.5 ± 4.0a | 0.29 ± 0.04 | −0.06 ± 0.01 | 0.3 ± 0.01 |
| DMMCBI–water | −1.0 ± 0.05 | −8.0 ± 3.0 | −3.5 ± .5 | 0.05 ± 0.01 | 0.2 ± 0.01 | −0.01 ± 0.002 |
| DMMCBI–PG | −3.0 ± 0.5a | −7.0 ± 2.0a | –b | 0.25 ± 0.06 | −0.24 ± 0.02 | –b |
| DMMCBI–ethanol | −9.0 ± 0.04 | Two peaks at 84°C and 88°C | –b | 0.7 ± 0.3 | − | –b |
| DMMCBI–PEG 400 | +6.0 ± 0.5 | +2.0 ± 0.6 | –b | 0.4 ± 0.03 | −0.07 ± 0.01 | –b |
| TBDOC–water | −9.0 ± 1.6 | −10.0 ± 2.0a | –b | No change | 0.01 ± 0.001 | –b |
| TBDOC–PG | –b | Merger of T m1 and T m2 at 70°C | –b | –b | − | –b |
| TBDOC–ethanol | +9.0 ± 0.8a | +12.0 ± 0.4a | +4.5 ± 0.08a | 0.3 ± 0.09 | −0.8 ± 0.1 | No change |
| TBDOC–PEG 400 | No change | No change | –b | 0.5 ± 0.03 | −0.01 ± 0.005 | –b |
SD standard deviation
aStatistically different compared to no treatment at 95% confidence interval (p < 0.05)
bMissing peak