Fig. 2.

a Alignment of segments of human and mouse Inpp5b enzyme encoded by exons 7 and 8. The segments corresponding to exons 7 and 8 are shaded as indicated. b Alignment of human and mouse exons 7, the portion of human intron 7 homologous to mouse exon 7, and exon 8. Segments are shaded with the same patterns used in a, indicating the various portions of exon 7 and exon 8. The location of primers discussed in the text is shown. The bent arrow indicates the approximate location of the transcriptional start of the transcripts generated from the internal promoter in mouse exon 7 and the analogous region in human intron 7