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In vitro MRI of superparamagnetic iron oxide-labeled porcine pancreatic islets.
A. Gradient echo T2*-weighted images of 500 islets suspended in 1% agarose phantom show decreased signal intensity of labeled islets compared to unlabeled islets.
B. T2 relaxation rates (1/T2) of labeled and unlabeled islets were 12.98 ± 0.01 sec-1 and 1.002 ± 0.24 sec-1, respectively (*p = 0.001). Islets were labeled for 48 hours in medium containing 100 µg Fe/mL of Resovist.
