Table 3. Cytotoxicity of Mononuclear Cells from HCC-Bearing and Normal Rats Against Variable Target Cells.
| Target Cells | ||||
|---|---|---|---|---|
| YAC-1 | P815(−) | P815(+) | Autologous HCC Cells | |
| HCC-bearing rat (n = 3) | ||||
| TIL | 16 ± 4* | 0 | 0 | 0 |
| Liver | 55 ± 10† | 1 ± 1 | 26 ± 5 | 0 |
| Spleen | 196 ± 32† | 2 ± 1 | 26 ± 6 | 0 |
| Normal rat (n = 3) | ||||
| Liver | 246 ± 52 | 1 ± 1 | 10 ± 5 | ND |
| Spleen | 337 ± 43 | 2 ± 2 | 31 ± 8 | ND |
Note: Cytotoxicities are shown in mean ± SD (LU20/107 effector cells). Abbreviations: ND, Not determined.
P < .01 vs liver and spleen in HCC-bearing rats.
P < .05 vs liver and spleen in normal rats.