Table 6.
Relative incidences of AVF failure according to MMP genotypes in HD patients
| Genotype | Total Observations (patient-months) | Episodes (times) | Episode/Patient-Months | P |
|---|---|---|---|---|
| Total | 29,727.83 | 268 | 1/110.9 | |
| MMP-1 −1607 1G/2G | ||||
| (1) 2G2G | 15,353.67 | 123 | 1/124.8 | P = 0.017 |
| (2) 2G1G | 11,340.07 | 94 | 1/120.6 | |
| (3) 1G1G | 3034.10 | 51 | 1/59.5 | |
| MMP-3 −1612 5A/6A | ||||
| (1) 5A5A | 574.93 | 3 | 1/191.6 | P = 0.226 |
| (2) 5A6A | 6194.13 | 43 | 1/144.05 | |
| (3) 6A6A | 22,958.77 | 222 | 1/103.4 | |
| MMP-9 −1562 C/T | ||||
| (1) CC | 21,862.9 | 219 | 1/99.8 | P = 0.031 |
| (2) CT | 7483.17 | 48 | 1/155.9 | |
| (3) TT | 381.77 | 1 | 1/381.8 | |
| MMP-1,-3,-9 | ||||
| (1) 1G1G/6A6A/CC | 960.2 | 34 | 1/28.2 | P < 0.001 |
| (2) 2GnG/5ANA/TXa | 1707.9 | 3 | 1/569.3 | |
| (3) other genotypes | 27,059.73 | 231 | 1/117.1 |
a
2GnG represents 2G2G or 2G1G (n = 1 or 2), 5ANA represents 5A5A or 5A6A (n = 5 or 6), TX represents TT or TC (X = T or C).