Table 2.
Relationship between tertiles of lipid parameters and long-term outcomes
Parameters | All-Cause Mortality |
CVD Mortality |
Kidney Failure |
|||
---|---|---|---|---|---|---|
Unadjusted | Adjusteda | Unadjusted | Adjusteda | Unadjusted | Adjusteda | |
TC | ||||||
tertile 1 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
tertile 2 | 1.29, 0.92 to 1.82 | 1.13, 0.79 to 1.61 | 1.12, 0.73 to 1.71 | 0.86, 0.55 to 1.36 | 1.11, 0.90 to 1.36 | 0.95, 0.77 to 1.18 |
tertile 3 | 1.35, 0.96 to 1.90 | 1.05, 0.73 to 1.51 | 1.11, 0.72 to 1.71 | 0.81, 0.51 to 1.29 | 1.04, 0.85 to 1.8 | 0.94, 0.76 to 1.17 |
NHDL-C | ||||||
tertile 1 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
tertile 2 | 1.39, 0.98 to 1.97 | 1.16, 0.80 to 1.66 | 1.29, 0.89 to 1.98 | 0.98, 0.62 to 1.53 | 1.23, 0.99 to 1.51 | 1.17, 0.94 to 1.45 |
tertile 3 | 1.58, 1.12 to 2.23 | 1.12, 0.78 to 1.60 | 1.24, 0.80 to 1.93 | 0.82, 0.52 to 1.30 | 1.18, 0.96 to 1.45 | 1.01, 0.80 to 1.25 |
TG | ||||||
tertile 1 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
tertile 2 | 1.03, 0.73 to 1.44 | 0.91, 0.64 to 1.29 | 1.32, 0.87 to 2.03 | 1.27, 0.82 to 1.97 | 0.88, 0.72 to 1. 09 | 0.89, 0.71 to 1.10 |
tertile 3 | 1.18, 0.85 to 1.65 | 0.94, 0.66 to 1.34 | 1.11, 0.71 to 1.74 | 0.96, 0.60 to 1.54 | 1.04, 0.85 to 1.27 | 0.99, 0.80 to 1.23 |
HDL-C | ||||||
tertile 1 | 1.38, 0.98 to 1.95 | 1.17, 0.78 to 1.74 | 1.26, 0.82 to 1.91 | 1.04, 0.64 to 1.70 | 1.44, 1.18 to 1.78 | 1.10, 0.85 to 1.42 |
tertile 2 | 1.39, 0.99 to 1.96 | 1.34, 0.93 to 1.95 | 1.03, 0.67 to 1.60 | 0.98, 0.61 to 1.57 | 1.17, 0.95 to 1.44 | 1.04, 0.87 to 1.38 |
tertile 3 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
Data presented as HR, 95% CI. HRs are per mg/dl increase for TC, HDL-C, and NHDL-C and per unit change in log-transformed TG.
Models adjusted for randomization assignments to protein diets and BP strata, age, race, gender, body mass index, systolic BP, history of CVD or diabetes, current cigarette smoking, proteinuria, etiology of kidney disease, and GFR.