Table 3.
Relationship between lipid parameters as continuous variables and long-term outcomes
| Parameter | All-Cause Mortality |
CVD Mortality |
Kidney Failure |
|||
|---|---|---|---|---|---|---|
| Unadjusted | Adjusteda | Unadjusted | Adjusteda | Unadjusted | Adjusteda | |
| TC | 1.03, 1.0 to 1.06 | 1.02, 0.98 to 1.05 | 1.02, 0.98 to 1.06 | 1.0, 0.96 to 1.04 | 1.01, 0.99 to 1.03 | 1.01, 0.98 to 1.03 |
| NHDL-C | 1.04, 1.01 to 1.07 | 1.01, 0.98 to 1.05 | 1.02, 0.98 to 1.06 | 0.99, 0.95 to 1.03 | 1.02, 0.996 to 1.03 | 1.01, 0.99 to 1.03 |
| TG | 1.23, 0.99 to 1.53 | 1.02, 0.79 to 1.31 | 1.13, 0.83 to 1.50 | 0.97, 0.70 to 1.32 | 1.06, 0.92 to 1.21 | 1.02, 0.86 to 1.19 |
| HDL-C | 0.92, 0.83 to 1.02 | 1.02, 0.91 to 1.14 | 0.98, 0.86 to 1.1 | 1.09, 0.95 to 1.26 | 0.93, 0.87 to 0.99 | 0.98, 0.91 to 1.06 |
Data presented as HR, 95% CI. HRs are per 10-mg/dl increase for TC, HDL-C, and NHDL-C and per unit change in log-transformed TG.
a
Models adjusted for randomization assignments to protein diets and BP strata, age, race, gender, body mass index, systolic BP, history of CVD or diabetes, current cigarette smoking, proteinuria, etiology of kidney disease, and GFR.