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. 2010 Nov;24(11):4459–4466. doi: 10.1096/fj.10-162347

Table 2.

MIF-knockout mice have functionally similar peripheral immune systems

Parameter C57Bl/6 MIF−/−
Proliferation (CPM)
    MOG35–55 2.3 × 104±0.6 2.2 × 104±0.7
    Anti-CD3 5.0 × 104±0.6 4.4 × 104±0.3*
Cytokines (ng/ml)
    IL-10 1.8±1.9 9.2±8.9
    IFN-γ 16.4±17.5 7.8±3.1
    IL-17 1.4±0.7 1.1±0.2
Leukocytes (%)
    CD4 22.3±2.0 21.3±2.5
    CD8 18.2±0.5 19.5±0.9
    CD19 53.2±4.2 51.0±0.8
    CD11c 1.4±0.2 1.45±0.5
    CD11b 8.8±0.4 9.4±0.7
    CD4/CD25 4.2±0.2 5.0±0.4*
    Foxp3 3.8±0.2 4.6±0.3*
*

P < 0.05.