Figure 2 Slow-wave energy and slow-wave activity during chronic partial sleep deprivation for the DQB1*0602 groups

Mean (±SEM) hourly slow-wave energy (SWE) and slow-wave activity (SWA) as a percentage of baseline at the same corresponding hour derived from the C3 (A, B), Fz (C, D), or O2 (E, F) channels at partial sleep deprivation/restriction night 1 (SR1) and partial sleep deprivation/restriction night 5 (SR5) for hour 1 (H1) and hour 2 (H2) for DQB1*0602-negative subjects (open circles) and DQB1*0602-positive subjects (closed circles). SWE and SWA increased from SR1 to SR5 for the C3 and Fz channels (denoted by *, p < 0.05). There were no group differences or differential changes across nights. In some records, EEG signal quality was insufficient or contained too much artifact for reliable power spectral analysis. Thus, the final sample sizes were as follows: for SR1 and SR5 C3, DQB1*0602-negative (n = 72) and -positive (n = 28) subjects; for SR1 and SR5 Fz, DQB1*0602-negative (n = 72) and -positive (n = 27) subjects; for SR1 and SR5 O2, DQB1*0602-negative (n = 72) and -positive (n = 26) subjects.