Table 1.

Studies of HRP-2 performance compared to microscopy, in P. falciparum endemic areas.

Reference	Location	Study population	Transmission (prevalence of positive blood smear in the study population)	Sensitivity	Specificity
Beadle [8]	Kenya	Children aged 9 to 14 years	Hyperendemic (86%)	87%	88%
Swathout[11]	Democratic Republic of Congo	Symptomatic children aged 6-59 months	Highly endemic and seasonal	100%	52%
Huong [9]	Vietnam	Symptomatic and control individuals aged 4-60 years	Hyperendemic	96%	100%
Guthmann [7]	Uganda	Symptomatic individuals	Hyperendemic (57%)	97%	88%
Williams [12]	Tanzania	Symptomatic individuals of all age	Hyperendemic (32%)	94%	89%
Shiff [10]	Tanzania	na	Holoendemic	89%	88%

na = not applicable