Table 1.
Proteins quantified with more than 1.5 fold changes, with IPI numbers, protein names, average ratios and S.D. listed (Peptides used for the quantification of individual proteins are listed in Table S2).
| IPI Number | Protein Name | Ratio (treated/untreated) |
|---|---|---|
| A. Histones and HMG | ||
| IPI00026272.1 | Histone H2A type 1-B | 2.52 ± 0.28 |
| IPI00171611.5 | H3 histone family, member M | 2.67 ± 0.93 |
| IPI00217465.4 | Histone H1.2 | 2.75 ± 0.56 |
| IPI00018534.3 | Histone H2B | 3.39 ± 0.39 |
| IPI00453473.5 | Histone H4 | 3.48 ± 1.09 |
| IPI00419258.3 | High mobility group protein B1 | 0.52 ± 0.04 |
| B. hnRNPs | ||
| IPI00216049.1 | hnRNP K, splice isoform 1 | 1.82 ± 0.28 |
| IPI00028888.1 | hnRNP D0, splice isoform 1 | 1.85 ± 0.33 |
| IPI00025054.1 | hnRNPU, splice isoform long | 1.97 ± 0.02 |
| IPI00176692.7 | PREDICTED: similar to hnRNP A1 | 2.19 ± 0.72 |
| IPI00334587.1 | hnRNP A/B, splice isoform 4 | 2.51 ± 0.34 |
| IPI00027834.3 | hnRNP L, isoform a | 2.59 ± 0.42 |
| IPI00171903.1 | hnRNP M, isoform a | 3.01 ± 0.81 |
| IPI00334587.1 | hnRNP A/B, splice isoform 2 | 3.18 ± 0.59 |
| IPI00216592.1 | hnRNP C1/C2, splice isoform C1 | 3.38 ± 0.47 |
| IPI00027569.1 | hnRNP C-like 1 | 3.97 ± 0.39 |
| IPI00215965.1 | hnRNP A1, isoform b | 4.15 ± 0.30 |
| IPI00386854.5 | hnRNP A2B1 protein | 4.38 ± 0.87 |
| IPI00396378.3 | hnRNP A2/B1, splice isoform B1 | 4.47 ± 0.23 |
| C. translation related factors | ||
| IPI00023048.3 | Elongation factor 1δ | 0.54 ± 0.13 |
| IPI00005154.1 | Structure-specific recognition protein 1 | 0.56 ± 0.04 |
| IPI00216587.8 | 40S ribosomal protein S8 | 0.64 ± 0.05 |
| D. Enzymes | ||
| IPI00008475.1 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 0.49 ± 0.15 |
| IPI00103732.1 | Thymidylate synthase | 0.52 ± 0.05 |
| IPI00218371.3 | Ribose-phosphate pyrophosphokinase III | 0.54 ± 0.14 |
| IPI00101405.1 | Farnesyl diphosphate synthase | 0.60 ± 0.02 |
| IPI00025874.2 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit precursor | 0.63 ± 0.17 |
| IPI00155168.2 | Protein tyrosine phosphatase, receptor type, C | 0.64 ± 0.09 |
| IPI00020454.1 | Deoxycytidine kinase | 0.66 ± 0.06 |
| IPI00027382.1 | Serine/threonine-protein kinase PAK 3, splice isoform 2 | 0.67 ± 0.02 |
| IPI00014808.1 | Platelet-activating factor acetylhydrolase IB γ subunit | 0.67 ± 0.02 |
| IPI00305978.4 | Aflatoxin B1 aldehyde reductase member 2 | 0.67 ± 0.09 |
| IPI00029997.1 | 6-phosphogluconolactonase | 0.67 ± 0.14 |
| IPI00011118.2 | Ribonucleoside-diphosphate reductase M2 subunit | 1.62 ± 0.24 |
| IPI00022314.1 | Superoxide dismutase [Mn], mitochondrial precursor | 2.17 ± 0.69 |
| E. Others | ||
| IPI00007423.1 | Acidic leucine-rich nuclear phosphoprotein 32 family member B | 0.51 ± 0.04 |
| IPI00003527.4 | Ezrin-radixin-moesin-binding phosphoprotein 50 | 0.55 ± 0.06 |
| IPI00027430.1 | Leukosialin precursor | 0.57 ± 0.14 |
| IPI00411356.5 | Vacuolar sorting protein 4a | 0.60 ± 0.02 |
| IPI00002214.1 | Importin α2 subunit | 0.60 ± 0.14 |
| IPI00004656.1 | β2-microglobulin precursor | 0.62 ± 0.02 |
| IPI00033494.3 | Myosin regulatory light chain | 0.64 ± 0.05 |
| IPI00027493.1 | 4F2 cell-surface antigen heavy chain | 0.65 ± 0.01 |
| IPI00010133.1 | Coronin-1A | 0.66 ± 0.04 |
| IPI00006932.1 | LUC7-like 2 | 0.66 ± 0.12 |
| IPI00301263.2 | CAD protein | 0.67 ± 0.05 |
| IPI00027341.1 | Macrophage capping protein | 0.67 ± 0.10 |
| IPI00298363.2 | Far upstream element-binding protein 2 | 1.62 ± 0.10 |
| IPI00215638.5 | ATP-dependent RNA helicase A | 1.58 ± 0.14 |
| IPI00017617.1 | Probable ATP-dependent RNA helicase DDX5 | 1.60 ± 0.37 |
| IPI00024913.1 | Splice isoform long of ES1 protein homolog, mitochondrial precursor | 1.63 ± 0.26 |
| IPI00017297.1 | Matrin-3 | 1.64 ± 0.31 |
| IPI00479786.2 | KH-type splicing regulatory protein | 1.78 ± 0.20 |
| IPI00220740.1 | Nucleophosmin, splice isoform 2 | 1.89 ± 0.48 |
| IPI00418471.5 | Vimentin | 1.97 ± 0.83 |
| IPI00005198.2 | Interleukin enhancer-binding factor 2 | 2.23 ± 0.15 |
| IPI00221354.1 | RNA-binding protein FUS, splice isoform short | 2.34 ± 0.56 |
| IPI00304596.3 | Non-POU domain-containing octamer-binding protein | 2.35 ± 0.52 |
| IPI00179964.5 | Polypyrimidine tract-binding protein 1, splice isoform 1 | 2.40 ± 0.63 |
| IPI00430812.4 | Zinc finger protein 9 | 2.70 ± 1.42 |
| IPI00301936.3 | ELAV-like protein 1 | 2.97 ± 0.69 |
| IPI00010740.1 | Splice isoform long of splicing factor, proline- and glutamine-rich | 3.75 ± 0.88 |