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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Eur J Neurosci. 2010 Aug 19;32(5):819–825. doi: 10.1111/j.1460-9568.2010.07359.x

Figure 5. IL-6 receptor antisense prevents exercise-induced hyperalgesia.

Figure 5

In rats that received antisense ODN to gp130 (open squares) for 3 days prior and 3 days after exercise, hyperalgesia in the exercised leg was significantly less than in exercised leg of rats receiving mismatch ODN to gp130 (filled squares). There was a significant effect of treatment in the contralateral limbs (two-way ANOVA F1,60 = 6.5; P = 0.021), with a significant difference only at the 24 h time point (Bonferroni post-hoc test, P<0.001).