Table 4.
Reported clinical characteristics of patients with femoral insufficiency fractures
| Study | Femoral insufficiency fractures | Bilateral insufficiency fractures | Prodrome of pain | Mean duration of bisphosphonate use (years) | Mean age (years) | Insufficiency fractures identified with no history of bisphosphonate use |
|---|---|---|---|---|---|---|
| Odvina et al., 2005 [46] | 5 | 2 | – | 5.6 (3–8) | 60.0 (49–68) | – |
| Goh et al., 2007 [26] | 6 | 3 | 5 | 4.2 (2.5–5) | 66.9 (55–82) | 0 |
| Kwek et al., 2008 [33] | 17 | 9 | 13 | 4.4 (2–10) | 66.1 (53–82) | 0 |
| Lenart et al., 2008 [35] | 10 | 2 | – | 7.3 (5.5–9) | 70.4 (55–83) | 3 |
| Neviaser et al., 2008 [45] | 19 | – | – | 6.9 | 69.5 | 1 |
| Sayed-Noor and Sjoden, 2008 [56] | 1 | 1 | 1 | 7.0 | 72.0 | – |
| Capeci and Tejwani, 2009 [16] | 7 | 7 | 4 | 8.6 (5–13) | 61.0 (53–75) | – |
| Sayed-Noor and Sjoden, 2009 [57] | 2 | 1 | 2 | 9.0 | 66.5 | – |
| Schneider, 2009 [59] | 3 | – | 2 | 7.3 (6–9) | 63.3 (59–66) | – |
| Aspenberg, 2008 [6] | 1 | 1 | 1 | 9.0 | 57.0 | – |
| Edwards et al., 2010 [23] | 1 | 1 | 1 | 6.0 | 60.0 | – |
| Koh et al., 2010 [30] | 16 | 0 | 7 | 4.5 (2–7) | 68.0 (53–92) | – |
| Current study | 41 | 18 | 29 | 7.1 (4–11) | 73.7 (67–85) | 0 |
* The exact number in the literature is unknown owing to multiple publications from the same patient populations; numbers in parentheses denote ranges; – = data not reported.