Table 1.
Baseline characteristics of participants
Characteristic | Participants with type 2 diabetes | Controls | |||||
---|---|---|---|---|---|---|---|
Baseline | After 8 weeks of sulodexide | p a | Baseline | p b | After 8 weeks of sulodexide | p c | |
n = 10 | n = 10 | n = 10 | n = 10 | ||||
Age (years) | 51.9 ± 8.4 | 51.9 ± 8.4 | p = NS | 56.3 ± 8.5 | p = NS | 56.3 ± 8.5 | p = NS |
Duration of diabetes (years) | 5.1 ± 5.6 | 5.1 ± 5.6 | p = NS | ||||
BMI (kg/m2) | 29.7 ± 5.5 | 29.6 ± 5.3 | p = NS | 27 ± 2.1 | p = NS | 26.9 ± 1.8 | p = NS |
SBP (mmHg) | 141 ± 14 | 139 ± 18 | p = NS | 135 ± 15 | p = NS | 141 ± 27 | p = NS |
DBP (mmHg) | 87 ± 8 | 84 ± 9 | p = NS | 82 ± 8 | p < 0.05 | 81 ± 6 | p = NS |
Glucose (mmol/l) | 7.1 ± 2.0 | 7.3 ± 2.4 | p = NS | 4.9 ± 0.4 | p = 0.002 | 5.2 ± 0.6 | p = NS |
HbA1c (%) | 7.1 ± 1.2 | 7.1 ± 1.2 | p = NS | 5.6 ± 0.3 | p < 0.001 | 5.5 ± 0.2 | p = NS |
TC (mmol/l) | 5.6 ± 1.0 | 5.3 ± 1.4 | p = NS | 6.3 ± 1.3 | p = NS | 5.5 ± 0.9 | p = NS |
LDL-C (mmol/l) | 3.4 ± 0.8 | 3.1 ± 1.3 | p = NS | 4.4 ± 1.1 | p = NS | 3.5 ± 1.0 | p = NS |
HDL-C (mmol/l) | 1.1 ± 0.3 | 1.0 ± 0.3 | p = NS | 1.4 ± 0.1 | p = 0.001 | 1.4 ± 0.3 | p = NS |
TG (mmol/l) | 2.0 (1.4–3.5) | 2.1 (1.1–3.0) | p = NS | 1.0 (0.9–1.3) | p = 0.001 | 1.3 (0.8–1.4) | p = NS |
CRP (mg/l) | 1.9 (0.5–5.5) | 1.5 (0.5–4.4) | p = NS | 1.2 (0.5–1.4) | p < 0.05 | 2.6 (0.8–14) | p = NS |
Values expressed as means ± SD
Triacylglycerol and CRP values are presented as median (interquartile range) due to skewed distribution
DBP, diastolic blood pressure; HR, heart rate; SBP, systolic blood pressure; TC, total cholesterol; TG, triacylglycerols
aDiabetes patients at baseline vs diabetes patients after 8 weeks of sulodexide
bBaseline diabetes patients vs baseline controls
cBaseline controls vs control participants after 8 weeks of sulodexide