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EBCTCG data for approximation of chemotherapy benefit in patients under 50 years with primary breast cancer [22]
| Treatment | HR recurrence years 0–4 | HR breast cancer mortality |
|---|---|---|
| CMF vs. no CT | 0.56 (0.05) | 0.68 (0.05) |
| Anthracyclines vs. CMF | 0.84 (0.05) | 0.81 (0.05) |
| Taxanes vs. anthracyclines | 0.84 (0.04) | 0.86 (0.05) |
| Taxanes vs. no CI (multiplication of 3 RRs) | 0.38 (0.07) | 0.46 (0.08) |
| 2p < 0.00001 | 2p < 0.00001 |
RR = Relative risk.
