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The developmental potential of neural crest-derived stem cells. Neural crest stem cells can generate neural (neurons and glias) and mesodermal progeny (adipocytes, chondrocytes, osteocyte and smooth muscle cells) when various extracellular signals are present. BMP2: bone morphogenetic protein 2; NRG: neuregulin; TGF-β: transforming growth factor-β; BDNF: brain derived neurotrophic factor; Dexa: dexamethasone.
