Table I.

P. aeruginosa PMM/PGM Structures Used for Computational Solvent Mapping

Protein	PDB ID	Description
WT complex with G1P	1P5D	Phosphorylated protein with bound substrate in closed conformation
WT complex with G6P	1P5G	Phosphorylated protein with bound substrate in closed conformation
WT complex with M1P	1PCJ	Phosphorylated protein with bound substrate in closed conformation
WT complex with M6P	1PCM	Phosphorylated protein with bound substrate in closed conformation
WT complex with X1P	2H5A	Phosphorylated protein with bound ligand (inhibitor) in closed conformation
WT complex with R1P	2H4L	Phosphorylated protein with bound ligand (slow substrate) in closed conformation
S108D complex with G16P	2FKM	Dephosphorylated protein with bound intermediate in closed conformation
WT complex with G16P	2FKF	Phosphorylated protein with bound intermediate in half-closed conformation
WT apo-enzyme	1K35	Phosphorylated protein in open conformation
S108A apo-enzyme	1K2Y	Dephosphorylated protein in open conformation