Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hydrogen bond distances in Å reveal the movement of the carbapenem's carbonyl oxygen between the backbone nitrogens of Ser70 (black) and Thr237 (red) during time. Letter designations (a–h) correspond to the hydrogen bonds present in Figure 4. A. KPC-2 and imipenem; B. Trp105Leu variant and imipenem; C. KPC-2 and doripenem; and D. Trp105Leu and doripenem.
