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A, chemical structure of RXP407, showing residue positions in the context of active site binding regions. B, close up of ACE N domain active site showing RXP407 and residues interacting with it. RXP407 is shown in wheat; the zinc and chloride ions are shown as green and red spheres, respectively; and the omit map for the RXP407 at 1σ is shown in dirty pink. Hydrogen bonds identified by HBPLUS (32) are shown as lines.
