Figure 4.

UDG-BER in vitro activities for nuclear extracts prepared from select tissues and cell types. Results are presented as means (±SEM) of three replicate assays for each of three nuclear protein extract preparations. Nuclear extracts were prepared from C57Bl/6 (open bars), CD1 (hatched bars) and B₆D₂F₁ (closed bars) male mice. (a) Significantly higher UDG-BER activity than all other tissues and cell types. (b) Significantly higher UDG-BER activity than brain. (c) Significantly higher UDG-BER activity than liver. (d) Significantly higher UDG-BER activity than small intestine and thymocytes.