Figure 2.—

Simulation results for two causative SNPs, where both are chosen at random. (A–C) Rank of the top-ranking causative SNP (blue) and the second-ranking causative SNP (orange) under (A) the “additive” genetic model, (B) the “or” model, and (C) the “xor” model. (D–F) Maximum distance to nearest causative SNP among SNPs with greater association than the more weakly associated causative SNP under (D) the additive genetic model, (E) the or model, and (F) the xor model. Colors indicate whether two, one, or none of the causative SNPs were found significant at the Bonferroni threshold. Only results where at least one SNP was found significant were included in the analysis.