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Heterozygous and homozygous gene deletion. (A) Histology of β-gal–stained bladders from iβ1+/fl and iβ1fl/− mice that received 1 mg tamoxifen daily for 28 days. (B) Quantification of β-gal positive cells from iβ1+/fl and iβ1fl/− mice exposed to 1 mg tamoxifen daily for 28 days. (C) Western blot for β1 integrin on bladder lysates from iβ1fl/− and iβ1+/fl mice. (D) Western blot for β1 integrin bladder lysates from β1+/− and β1fl/fl mice.
