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Deletion of β1 integrin in β1e3 mice. (A) Survival curve for iβ1fl/−, iβ1+/fl, iβ1e3/e3, and β1e3/e3 mice from the first injection through 3 months after final injection. (B) PCR of recombination (e3ex) and intact allele (e3int) in the iβ1e3/e3 and β1e3/e3 mouse bladders. (C) Western blot analysis of bladder from iβ1e3/e3 and β1e3/e3 adult mice exposed to 1 mg tamoxifen daily for 28 days.
