Restriction endonuclease
analysis to determine methylation status of MAGGY (A)
and MGR583 (B) sequences in M.grisea isolates
from various monocot plants. Genomic DNA was extracted from mycelia,
digested with isoschizomers HapII (H) and Msp I
(M), and hybridized with a 5.4 kb XhoI fragment
of MAGGY. HapII is sensitive to cytosine methylation
but MspI is not. Southern blots of isolates 7,
8 and 9 were overexposed in (A) due to the low copy
numbers of MAGGY-related sequences in them. 1, IN77-16-1-1 (isolated
from foxtail millet in India); 2, NNSI2-1-1 (foxtail millet in Japan);
3, GFSI1-7-2 (foxtail millet in Japan); 4, IN77-46-1-3 (rice in
India); 5, 1601-3 (rice in Japan); 6, 1836-3 (rice in Japan); 7,
IN77-28-1-1 (P.repens in India); 8, STPM4-3-3 (P.miliaceum in Japan); 9, YNPM2-2-1 (P.miliaceum in
Japan).