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Outflow block in a canine hepatic homograft 4 days after transplantation. The centrilobular sinusoids (arrows) are distended with blood, and adjacent hepatocytes are necrotic. There is accumulation of fat in the liver cells of the middle lobular zone. Only hepatocytes adjacent to the portal tracts (P) are normal. Hematoxylin-eosin; ×40.
