Fig. 32.

Tissues from the longest surviving orthotopic canine liver homograft. This animal had normal liver function almost 1 year after operation. A, biopsy at 120 days. There is evidence of regeneration of hepatocytes at the periphery of the lobule, but no other abnormality. Hematoxylin-eosin; ×40. B, biopsy 82 days after all immunosuppressive drugs had been stopped. The homograft appears normal. Electron micrograph; ×1,600. C, biopsy 182 days after all immunosuppressive drugs had been withdrawn and 302 days after transplantation. The lobular reticulin pattern appears normal. Reticulin stain; × 30.