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Case 5 of Colorado series; orthotopic homograft at 23 days. A, there is centrizonal and midzonal necrosis of liver cells. Only those near portal tracts (P) survive. Some hemorrhages are present in central zones (arrow). Hematoxylin-eosin; ×30. B, There is collapse of the supporting centrilobular reticulin where liver cells have undergone necrosis. P, portal tract. Reticulin stain; ×30.
