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. Author manuscript; available in PMC: 2010 Nov 8.
Published in final edited form as: J Immunol. 2008 Jul 15;181(2):1096–1102. doi: 10.4049/jimmunol.181.2.1096

FIGURE 4.

FIGURE 4

Intragraft gene expression after CD154 blockade in the following experimental groups: N/MR1, naive recipients; S/MR1, sensitized recipients. The latter group received no adjunctive (−) or adjunctive CD4-blocking (+Y) or CD4-depelting (+G) Ab. Cardiac allografts were harvested at day 4 or 7 and tissue RNA samples were subjected to quantitative RT-PCR as described in Materials and Methods. Target gene expressions were calibrated by their ratios against HPRT levels of the same sample. Average expression ratios in different treatment groups were plotted. n = 3–6/group;*, p < 0.05.