Table II.
KEGG pathway analysis of the gene list sensitive to CD154 blockade in naive recipients, but resistant to CD154 blockade in sensitized recipients
| KEGG Pathway | List | Array | z-score |
|---|---|---|---|
| Cell adhesion molecules | 34 | 129 | 4.38 |
| NK cel-mediated cytotoxicity | 27 | 112 | 3.36 |
| BCR signaling pathway | 17 | 64 | 3.11 |
| One carbon pool by folate | 6 | 15 | 3.02 |
| Hematopoietic cell lineage | 19 | 76 | 2.99 |
| Type I diabetes mellitus | 13 | 47 | 2.88 |
| Leukocyte transendothelial migration | 25 | 111 | 2.85 |
| Cytokine-cytokine receptor interaction | 42 | 220 | 2.53 |
| TCR signaling pathway | 20 | 92 | 2.36 |
| Apoptosis | 18 | 81 | 2.34 |
| Vascular endothelial growth factor signaling pathway | 16 | 70 | 2.33 |
| Fcε RI signaling pathway | 17 | 76 | 2.31 |
| Chronic myeloid leukemia | 16 | 74 | 2.08 |