TABLE 1.
Subject characteristics (n=400)
| Age, years (mean ± SD) | 50.4±15.1 |
| Sex, male/female, n (%) | 168 (42)/232 (58) |
| Medication | |
| None | 188 (47.0) |
| Short-acting bronchodilator on demand only | 65 (16.2) |
| Inhaled corticosteroids regularly | 151 (37.8) |
| Baseline FEV1, % predicted (mean ± SD) | 97.2±15.8 |
| Subjects with values <80% of predicted | 53 (13.2) |
| Baseline FEV1/FVC, % (mean ± SD) | 79.0±7.7 |
| Subjects with values <70% | 49 (12.3) |
| Symptoms present in the previous two weeks | 261 (65.2) |
| PC20, mg/mL | |
| <0.25 | 5 (1.2) |
| 0.25 to <2 | 42 (10.5) |
| 2 to <8 | 64 (16.0) |
| 8 to 16 | 64 (16.0) |
| >16 | 225 (56.2) |
Data presented as n (%) unless indicated otherwise. FEV1 Forced expiratory volume in 1 s; FVC Forced vital capacity; PC20 Provocative concentration of methacholine causing a 20% fall in FEV1