Table 3.
Univariate analysis of risk factors for each bacterial infection after OLTx
| Risk factor | Postoperative EMBI (n = 41) | No postoperative EMBIa (n = 52) | Significance level |
|---|---|---|---|
| Age (yr) | 34 ± 1.4 | 36 ± 1.4 | |
| Sex (male/female) | 21/20 | 16/36 | |
| Previous infectiona | 23% | 13% | |
| Previous immunosuppressive therapya | 28% | 17% | |
| Ascitesa | 61% | 47% | |
| Variceal bleedinga | 33% | 21% | |
| Hepatic encephalopathya | 42% | 28% | |
| Total bilirubin levela (mg/dl) | 21.9 ± 2.4 | 14.2 ± 1.8 | p < 0.05 |
| Prothrombin time (sec)b | 15.7 ± 0.5 | 16.7 ± 2.2 | |
| Total serum proteins (mg/dl)b | 6.5 ± 0.2 | 7.1 ± 0.2 | |
| Serum albumin (mg/dl)b | 3.1 ± 0.1 | 3.4 ± 0.1 | |
| Transferrin (μg/dl)b | 343 ± 15 | 345 ± 14 | |
| WBC count (cells/mm3)b | 8,799 ± 866 | 6,680 ± 520 | p < 0.05 |
| PMN cell count (cells/mm3)b | 6,223 ± 685 | 4,235 ± 341 | p < 0.05 |
| Lymphocytes (cells/mm3)b | 1,122 ± 140 | 1,242 ± 109 | |
| Lymphocyte T cells (cells/mm3)b | 604 ± 90 | 659 ± 50 | |
| Helper T lymphocytes (cells/mm3)b | 189 ± 26 | 189 ± 22 | |
| Suppressor T lymphocytes (cells/mm3)b | 423 ± 59 | 477 ± 33 | |
| Ratio of helper to suppressor T lymphocytesb | 2.87 ± 0.26 | 3.68 ± 0.33 | |
| IgG (mg/dl)b | 1,655 ± 129 | 1,343 ± 70 | p < 0.05 |
| IgM (mg/dl)b | 284 ± 30 | 316 ± 26 | |
| IgA (mg/dl)b | 372 ± 42 | 351 ± 27 | |
| C′3 (mg/dl) | 109 ± 10 | 123 ± 10 | |
| C′4 (mg/dl) | 18 ± 2 | 24 ± 3 | |
| CHIOOb | 48 ± 5 | 72 ± 6 | |
| PFB (mg/dl) | 32 ± 3 | 42 ± 8 | |
| Creatinine (mg/dl) | 2.3 ± 0.4 | 1.3 ± 0.3 | p < 0.001 |
a
Between first complaint and transplantation.
b
Preoperative evaluation.