Figure 2. Seven Single-Nucleotide Polymorphisms Associated With Select Echocardiographic Traits in Stage 1 and Replicated in Stage 2.
Individual studies are plotted against the individual effect sizes (β coefficients for continuous traits). The size of the box is inversely proportional to the estimated variance of the effect-size estimator. Horizontal lines are the confidence intervals corresponding to the P value threshold of 5×10−7. The vertical line indicates the value is consistent with no association. If a single-nucleotide polymorphism was not available in a study, there is no data point for that study. The diamond represents the meta-analytic effect size.