Table 2.

Scaling factors α for Pin1cat.

Free Enzyme.
Pin1cat residue2	α3	+/−4
Gln75	1.95	0.62
Glu76	1.95	0.46
Lys77	1.95	0.62
Enzyme-Substrate Complex5
Pin1cat residue2	α3	+/−4
Arg68	1.95	0.31
Arg69	1.95	0.29
Ser71	1.93	0.73
Ser72	1.93	0.56
Gln75	1.93	0.38
Lys77	1.94	0.90
Ser114	1.94	0.40
Ser115	1.95	0.35
Lys117	1.93	0.56
Gly123	1.94	0.34
Gly128	1.94	0.58
Gln129	1.94	0.53
Lys132	1.92	0.67
Ser154	1.94	0.61
Gly155	1.15	0.26
Ile158	1.94	0.60

¹Relaxation data collected at 11.7T and 14.1T

²α values are reported for exchanging residues if the uncertainty in α is less than 50%

³Values of R_ex used in calculating α were estimated from the fits of R2(ν_CPMG) data to the general Carver-Richards equation as R_ex = R2obs(33Hz) − R2_o

⁴Uncertainties in α are calculated by propagating the uncertainties in the fitted R2_o and R2obs(33Hz)

⁵Relaxation data collected at 11.7T and 16.9T