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. Author manuscript; available in PMC: 2010 Nov 8.
Published in final edited form as: Anal Chem. 2008 Oct 21;80(22):8694–8701. doi: 10.1021/ac800606w

Table 3.

A summary of identified proteins and peptides containing transmembrane (TM) regions in six digestion conditions. Proteins containing at least one transmembrane domain (TMD) are predicted by the TMHMM algorithm (see method). Peptides containing the sequences of the transmembrane region are identified and summarized in the second row. The last row of data represents the percentage of TMD peptides identified from the identified TMD proteins. Higher ratio of TMD peptide vs. TMD protein indicates higher representation of the transmembrane region in the particular digestion condition.

Tris RPG Tris IVS Tris PPS ACN IVS ACN PPS ACN RPG
TMD
Protein
556 476 430 422 324 213
TMD
Peptide
88 73 23 86 23 39
TMD
peptide/
TMD
Protein
15.8% 15.3% 5.3% 20% 4.9% 8.7%